Table 2 Application of CRISPR-Cas9 in insect pest resistant management
From: Emerging technological developments to address pest resistance in Bt cotton
Target insect | Target genes | Effects of CRISPR on the target insect | Reference |
|---|---|---|---|
H. armigera | Glutathione S-transferase (GST cluster gene) | Knockout of the GST cluster gene significantly increased the sensitivity to lambda-cyhalothrin | Jin et al. (2023) |
H.armigera, S.litura | GmUGT | Over-expression of the GmUGT gene is functionally involved in imparting resistance to leaf-chewing pests | |
P. gossypiella | PgABCA2 | Disruptive mutations in PgABCA2 increased the frequency of resistance to Cry2Ab | Fabrick et al. (2021) |
H. zea | HzABCA2 | Knockout of ABCA2 confers resistance to Cry2Ab | Fabrick et al. (2022) |
B. tabaci | lncD09, lncA07 | Knockout mutation of lncD09 and lncA07 confers the importance of jasmonic acid against sucking pest resistance | |
H. armigera | HaCAD-KO, HaABCC2-M, HaABCC3-M | Very high levels of resistance were observed to Cry1Ac | Liao et al. (2022) |
S. frugiperda | PBAN | The specific inhibition of PBAN in females has a major impact on mating | Ashok et al. (2023) |